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The methods and standards for carrying out meta-analyses have evolved in recent years. It has been found that meta-analyses are among the types of publications that usually receive a larger number of citations in the biomedical sciences. Because of the significant increase in the published scientific literature in recent years, there has also been an important growth in the number of meta-analyses for a large number of topics. Meta-analysis is a powerful tool to cumulate and summarize the knowledge in a research field. In the context of evidence-based medicine, meta-analyses provide novel and useful information, as they are at the top of the pyramid of evidence and consolidate previous evidence published in multiple previous reports. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist. PGB is partially supported by ELIXIR-GR, the Greek Research Infrastructure for data management and analysis in the biosciences. DAF is supported by research grants from Colciencias and VCTI. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: YG-G is supported by a PhD fellowship from Centro de Estudios Interdisciplinarios Básicos y Aplicados CEIBA (Rodolfo Llinás Program). PLoS Comput Biol 15(5):Įditor: Scott Markel, Dassault Systemes BIOVIA, UNITED STATESĬopyright: © 2019 Forero et al.
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Citation: Forero DA, Lopez-Leon S, González-Giraldo Y, Bagos PG (2019) Ten simple rules for carrying out and writing meta-analyses.